Eli Manning and Philip Rivers meet for the first time Sunday at Giants Stadium, with Manning looking to help New York avoid a fourth straight loss and Rivers trying to lead the Chargers to their first victory over a winning team.

When checking out NFL betting lines before making a pick, the Giants are pegged as 5-point favorites.

Manning had 10 touchdowns and two interceptions in New York’s 5-0 start, but threw three TDs and six interceptions over the last three games.

While Manning has played poorly the last three weeks, New York’s defense has been worse. The Giants were outscored 112-61 during that span, with opponents totaling 1,172 yards.

All of San Diego’s wins were against losing teams, with its defeats coming to contenders Denver, Baltimore, and Pittsburgh. The Chargers’ two straight victories came against lowly Kansas City and Oakland.

LaDainian Tomlinson has gone a career-high 13 straight games without gaining 100.

Get your NFL Odds in the Bodog Sportsbook!

NFL betting odds have the Niners listed as 4.5-point favorites.

Tennessee earned its first win last week, beating Jacksonville 30-13. Young completed 15 of 18 passes for 125 yards and a touchdown.

While Young was steady, the Titans’ first victory was really keyed by Johnson. He rushed for a franchise-record 228 yards on 24 carries and scored two touchdowns.

Johnson leads the league in rushing with 824 yards after entering last week fifth. His five runs of over 40 yards also lead the NFL.

San Francisco appears to be fairly healthy up front on defense, and that will be important as it tries to contain Johnson. The 49ers have the league’s second-ranked rush defense, allowing 84.9 yards per game.

Get your NFL Odds in the Bodog Sportsbook!

NFL betting lines have the Jags listed as 7-point home favorites.

After a 14-6 triumph at Washington, the Chiefs are seeking victories in consecutive road contests for the first time since 2007.

In seven games, the Chiefs’ offense has had 92 negative plays. Those are running and passing plays for minus yards, sacks, interceptions, fumbles lost, and offensive penalties. When it comes to negatives on offense, the Chiefs lead the league.

To say Kansas City has been banged up is an understatement. The Chiefs have had 35 different players start at least one game for the club in 2009. In fact, Kansas City hasn’t boasted the same 22 starters in back-to-back weeks all season.

The Chiefs are 2-5 ATS in their last seven meetings with the Jaguars.

Get your NFL Odds in the Bodog Sportsbook!

NFL betting odds have the Ravens listed as 3-point road favorites.

In the last meeting between these teams, penalties doomed the Ravens. They were flagged three times during Cincinnati's game-winning drive with a few minutes left on the clock. One of those penalties came when Ray Lewis popped receiver Chad Ochocinco after a pass sailed wide and Ochocinco was defenseless. Lewis was fined for the hit, and the extra yardage allowed Carson Palmer to throw a touchdown pass late to win it 17-14.

Carson Palmer is back and as good as ever, throwing for 1,608 yards and 13 touchdowns this year.

Get your NFL Odds in the Bodog Sportsbook!

Ryan has also been throwing the ball to the opposition at an alarming rate. He has seven interceptions through seven games.

The good news for the Falcons and Ryan is that this week they get to play the Washington Redskins, a team that is becoming a weekly joke.

NFL football betting lines have the Falcons currently listed as 10-point road favorites.

The Redskins are 3-12-3 ATS overall recently, primarily due to the fact that their skill players have yet to show much skill.

The two teams have met four times this decade with an even 2-2 split. The favorite covered in three of the four games, with the only exception coming when Washington won by two the last time they played in Atlanta.

Get your NFL Odds in the Bodog Sportsbook!

It could also wind up being huge in the national title race. Alabama coach Nick Saban meets his old team in a game that could send his current one to the SEC championship game. The Tide only has to win to secure a spot.

Or LSU could win and take control of the SEC West.

These two teams have combined to win three of the last four division titles. They’re standing in each other’s way once again.

College football betting lines have the Tide listed as 7.5-point favorites.

Last season, Alabama snapped a five-game losing streak to LSU with a 27-21 overtime win.

The defenses might be an even better storyline than the coaches this time. Alabama is fifth nationally in scoring defense, LSU is seventh.

Get your NCAA Football Odds in the Bodog Sportsbook!

Both are 4-1 in the Big Ten and a game back of unbeaten Iowa, which defeated Penn State earlier in the year and still must play Ohio State. A loss doesn’t eliminate either team from the league race, but it sure would make things difficult. A loss would almost certainly knock a team out of the BCS picture as well.

College football betting odds have the Nittany Lions listed as 4-point home favorites.

A year ago, the teams met under somewhat similar circumstances at Ohio Stadium, with both perfect in league play. Terrelle Pryor’s deep throw with 27 seconds left was picked off by Lydell Sargeant to seal the game.

The home team is 9-2 ATS in their last 11 meetings, while the Buckeyes are 1-4 ATS in their last five meetings in Penn State.

Get your NCAA Football Odds in the Bodog Sportsbook!

College football betting lines have the Broncos listed as a 21.5-point favorite.

Kellen Moore has thrown 24 TDs and just two interceptions this season. He’s helped the Broncos score 41.0 points per game, the nation’s third-best average.

Boise State also has the nation’s 10th-ranked defense and is 11th in allowing an average of 13.6 points. It has forced six fumbles and 13 interceptions for the nation’s fifth-best turnover ratio.

Boise State is searching for its eighth consecutive win over Louisiana Tech since dropping the inaugural meeting in 2001.

Moore threw for 325 yards and two touchdowns to lead Boise State to a 38-3 home win over Louisiana Tech last season.

Get your NCAA Football Odds in the Bodog Sportsbook!