Many think that Federer and Rafael Nadal will meet in the U.S. Open final for the first time. It’s the only Grand Slam tennis final in which they’ve never met.

Nadal is pegged at +650 to overcome his recent injuries to take the title.

Andy Murray is another solid bet this year. He has a match record of 53-8 this year and is listed at +333 to win.

Other notables include Novak Djokovic (+1100), who hasn’t been past the quarterfinals at any of this year’s major tournaments, and Andy Roddick (+1100), who is the only U.S. man seeded in the top 20.

Throw in Jo-Wilfried Tsonga (+4000) and Marat Safin and it is clear that Federer's road to another title won't be as easy as one might think.

Get your US Open Odds in the Bodog Sportsbook!

Age: 28

Country: Switzerland

2009 Match Record: 47-7

2009 Singles Titles: 4

Odds to win U.S. Open: +100

Career Singles Titles: 61

Major Titles: 15—U.S. Open (’04, ’05, ’06, ’07, ’08), Australian Open (’04, ’06, ’07), French Open (’09), Wimbledon (’03, ’04, ’05, ’06, ’07, ’09)

Last 5 U.S. Opens: ’08-Won Championship, ’07-W, ’06-W, ’05-W, ’04-W

Titles at the French Open and Wimbledon allowed him to tie, then break, Pete Sampras’ record of 14 Grand Slam championships. He has reached the final at 16 of past 17 majors and the semifinals at 21 consecutive Grand Slam tournaments.

Entered Madrid Open in May without a title this season, but has won four of past five tournaments.

The U.S. Open is his first Grand Slam tournament as a father: His wife, Mirka, gave birth to twin daughters in July.

Get your US Open Odds in the Bodog Sportsbook!

Federer said, "We named them Myla Rose and Charlene Riva and they are both healthy, and along with their mother they are doing great. This is the best day of our lives."

Roger and Mirka met in 2000 when they were competing for Switzerland in the Sydney Olympics. Mirka played on the WTA Tour and after an injury, she retired and became one of Federer's managers.

Be sure to get all your tennis betting in the Bodog Sportsbook today.

Roddick gave it a massive effort and in congratulating Federer he called him a "true champion."

"You played unbelievably today," Federer said to Andy after the match.

And to the crowd in attendance, Federer said: "My head is still spinning and this is an unbelievable feeling. It feels amazing and it's one of the greatest moments I've had in my career."

And the magic number is…15. Federer is the greatest tennis player in tennis history.

Get all your sports betting at Bodog.

Roddick’s major title, not quite six years ago, was also the last at any Grand Slam event for an American man, the country’s longest drought in the Open era, which began in 1968.

Murray (-330) is 6-2 against Roddick (+250), including a lopsided victory in their most recent meeting, in the final of a hard-court tournament at Doha, Qatar, in January.

This match could be decided by Roddick’s serve against Murray’s returns.

Federer is listed as a -1400 favorite to get to a record seventh consecutive Wimbledon final and record 20th career Grand Slam final.

UPDATE: Federer easily dispatched Tommy Haas to move onto the final.

Get your Wimbledon Odds in the Bodog Sportsbook!

The 6-foot-10 Croat has not been broken once in 79 service games this tournament and leads all players with 137 aces.

Still, Federer is a heavy favorite, listed at -1400 to win the match.

The quarterfinal round features players of eight nationalities, with five Grand Slam tournament winners and four former No. 1s.

In other matches Andy Murray (-1400) takes on Juan Carlos Ferrero (+675) of Spain.

On Court 1, two veterans will try to get back to the Wimbledon semifinals for the first time in four years. Andy Roddick, the runner-up to Federer in 2004-05, takes on Lleyton Hewitt, who won here in 2002.

The fourth matchup features the oldest remaining player against the youngest, with the 31-year-old Tommy Haas taking on 22-year-old Novak Djokovic.

UPDATE: Looks like Federer being the huge fave was the right thing for oddsmakers to do, he made quick (very quick) work of Karlovic, beating him in straight sets.

Get your WImbledon Odds in the Bodog Sportsbook!

It also elevates Andy Murray to the favorite in my opinion.

The Brit is currently 11/4 to win tennis' lone grass-court major. That's second to Federer (4/5), who has won this tournament five teams and might be poised to break Pete Sampras record of 14 Grand Slam titles as well as return to No. 1 in the world off his French Open championship. Federer should be the overwhelming favorite.

But Murray is the big winner of the Nadal news. That's because Murray, now seeded No. 2, was in the same half of the Nadal draw (and thus won't have to play Federer until a possible final). The Spaniard had reached the final at the All England Club in the past three years and routed Murray in straight sets in a 2008 quarterfinal.

Now the highest-rated possible semifinal opponent for Murray is Argentine Juán Martín del Potro, the world No. 5, who is a clay-courter and has only won two career matches at Wimbledon.

Perhaps most important is that Murray is 6-2 in his career against Federer, including two victories in two tries this year and four in a row. It's clear he has confidence against the Swiss star.

Murray also enters having just become the first British champion of the warm-up Queen's Club tournament in 71 years. It was his first-ever grass-court title and continued what has been a great year, with Murray going 40-6 with four titles (second in championships to Nadal).

"I'm playing very well just now," Murray said to reporters. "I feel physically strong."

Obviously history is against Murray, considering no British men's player has won this tournament since Fred Perry in 1936. But at 11/4, put some money down on history finally repeating itself. Think that would be big news in England?

Get all your Wimbledon odds at Bodog.

In a news conference today at the All England Club, Nadal told reporters that he is withdrawing from the popular tennis tournament because of tendinitis in his knees. All other Wimbledon competitors will take to the grass courts on Monday, June 25th.

"I'm just not 100 percent," the No. 1-ranked Nadal said. "I'm better than I was a couple of weeks ago, but I just don't feel ready."

That leaves Roger Federer, the favorite at 4/5 odds to win Wimbledon 2009.

Federer, listed at -500 on Sunday, was at his best, completely outplaying No. 23-seeded Robin Soderling (+350) of Sweden en route to a 6-1, 7-6 (1), 6-4 victory in a French Open final that lacked suspense but not significance.

Federer is now pegged as a +100 favorite to win Wimbledon this year.

On Saturday in the women's final Svetlana Kuznetsova took advantage of No. 1-ranked Dinara Safina's assorted errors and won the French Open final 6-4, 6-2. The 74-minute match ended, fittingly, with Safina's seventh double-fault.

Safina was the one who was supposed to finally make her breakthrough after losing in the women's final at last year's French Open and this year's Australian Open.

Federer lost to Rafael Nadal in the past three finals at Roland Garros, but the Spaniard is no longer around this year after being upset by Soderling in the fourth round.

Del Potro faces a monumental task against Federer as not only will he have the crowd against him but he has never won a set in five previous matches against the Swiss world number two.

In the other match, Gonzalez is the favorite at -155 but it is hard to bet against Soderling (+115) after the upsets he has pulled off in Paris. Get your French Open odds now.